Master Cleanse Forum - Master Cleanser Lemonade Diet

I've asked this before and I don't really expect that anyone has an answer for this. I'm not really looking for guesses, but scientific reasons based on actual experiences for why it is recommended to wait at least three months between cleanses.

Stanley Burroughs doesn't really seem to get into the reason/s behind this.

Has anyone come across anything pertaining to this online?

Thanks.

New Yorker